Xin-Xuan Dai; Ji-Long Hao; Dan-Dan Zhou; Si-Ying Teng; Peng Hui; Cheng-Wei Lu
Volume 21, Issue 12 , 2019, Pages 1-4
Abstract
Introduction: Bee sting to the cornea is a relatively rare environmental injury that can result in vision loss of different degrees. This study aimed to review the clinical features, pathogenesis, and management of keratopathy caused by corneal bee sting and present a case of keratitis with hypopyon ...
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Introduction: Bee sting to the cornea is a relatively rare environmental injury that can result in vision loss of different degrees. This study aimed to review the clinical features, pathogenesis, and management of keratopathy caused by corneal bee sting and present a case of keratitis with hypopyon and iridocyclitis secondary to bee sting injury without a retained stinger.Case Presentation: A 47-year-old man was presented for eyelid edema, severe pain, redness, and impaired vision following a corneal bee sting. On examination, we observed striate keratitis, focal infiltration with diffuse corneal edema, and iridocyclitis under the slit lamp. We also noted trace cells and empyema in the anterior chamber prompted by infection. No retained stinger was detected. A treatment strategy with corticosteroids in combination with broad-spectrum topical antibiotics started and the symptoms re- solved significantly. At a three-week follow-up, the cornea restored transparency without complications and visual acuity main-tained 20/20.Conclusions: Following bee sting injury, it is crucial to monitor the progression, manifestations, and development of inflamma- tion and infection. Individual timing, symptoms, severity, and complications vary in each case due to various compositions of bee venom. Therefore, assessment and careful follow-up of evolving manifestations may lead to better therapeutic decisions.
Cheng-Wei Lu; Zhi-Hua Cui; Xiao-Feng Qi; Om Prakash Pant; Cheng-Bo Lu; Ji-Long Hao; Dan-Dan Zhou
Volume 21, Issue 1 , 2019, Pages 1-5
Abstract
Introduction: Keratitis induced by type I hypersensitivity to metronidazole is rarely reported. In vivo confocal microscopy (IVCM)is a promisingmethod for the investigation of cornealmorphology under pathological conditions. The purpose of the present studywas to investigate the IVCM features of keratitis ...
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Introduction: Keratitis induced by type I hypersensitivity to metronidazole is rarely reported. In vivo confocal microscopy (IVCM)is a promisingmethod for the investigation of cornealmorphology under pathological conditions. The purpose of the present studywas to investigate the IVCM features of keratitis associated with anaphylaxis to metronidazole and review the literature regardingIVCM application to study drug-related changes in the cornea.Case Presentation: A 50-year-old woman with acute bilateral keratitis induced by anaphylaxis to intravenous metronidazole presented to the Department of Ophthalmology, the first affiliated hospital of Jilin University, Changchun, China in Jan 2018. She initially experienced photophobia, moderate conjunctival injection, and watery discharge after infusion of intravenous metronidazole. These symptoms gradually resolved one month after she was administered anti-allergic drugs. Corneal morphology related toanaphylaxis to metronidazole was investigated by IVCM before and after treatment. To our knowledge, this is the first reported caseof IVCM images of keratitis associated with anaphylaxis to metronidazole.Conclusions: In vivo confocal microscopy can allow objective evaluation of treatment response through cellular changes in thecornea and could provide good-quantity images of ocular surface tissues for follow-up
